- Microangiopathic Hemolytic Anemia (Coomb's negative) :- Haemolysis , Fragmentation of RBC's , Increased LDH (elevated due to intravascular hemolysis)
- Thrombocytopenia :- ( due to consumptions of platelets)
- Decreased renal function:-(due to deposits in the Renal Vasculature)
- Disturbed NEUROLOGICAL function:-characteristically diffuse and non focal eg-confusion,aphasia,alteration in consciousness
- Fever
clinical pentad of TTP
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