clinical pentad of TTP

  1. Microangiopathic Hemolytic Anemia (Coomb's negative) :- Haemolysis , Fragmentation of RBC's , Increased LDH (elevated due to intravascular hemolysis)
  2. Thrombocytopenia :- ( due to consumptions of platelets)
  3. Decreased renal function:-(due to deposits in the Renal Vasculature)
  4. Disturbed NEUROLOGICAL function:-characteristically diffuse and non focal eg-confusion,aphasia,alteration in consciousness
  5. Fever

No comments:

Post a Comment