sources of Alkaline Phosphatase-
- bone
- intestine
- liver
- placenta
importance of alkaline phosphatase in bone disesese:
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- Serum alkaline phosphatse is the most valuable enzyme for assessment of bone disesases and serves as index of osteoblastic activity.
- Increased level of alkaline phosphatase are seen in-
a.Pagets diseases:-level of alkaline phosphatase are higher in Pagets disease than in any other condition. (excpt hereditary hypophosphatasia).
b.Hyperparathyroidism:-serum alkaline phosphatase may be raised depending upon degree of involvement of bone.
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